Cardiovascular Events Are Not Associated with MTHFR Polymorphisms, But Are Associated with Methotrexate Use and Traditional Risk Factors in US Veterans with Rheumatoid Arthritis

OBJECTIVE: C677T and A1298C polymorphisms in the enzyme methylenetetrahydrofolate reductase (MTHFR) have been associated with increased cardiovascular (CV) events in non-rheumatoid arthritis (RA) populations. We investigated potential associations of MTHFR polymorphisms and use of methotrexate (MTX)...

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Main Authors: Davis, Lisa A., Cannon, Grant W., Pointer, Lauren F., Haverhals, Leah M., Wolff, Roger K., Mikuls, Ted R., Reimold, Andreas M., Kerr, Gail S., Richards, J. Steuart, Johnson, Dannette S., Valuck, Robert, Prochazka, Allan, Caplan, Liron
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4097095/
https://ncbi.nlm.nih.gov/pubmed/23547211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3899/jrheum.121012
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