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Vertebrate Limb bud formation is initiated by localized Epithelial to Mesenchymal Transition

Vertebrate limbs first emerge as small buds at specific locations along the trunk. Although a fair amount is known about the molecular regulation of limb initiation and outgrowth, the cellular events underlying these processes have remained less clear. We show that the mesenchymal limb progenitors a...

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Detalhes bibliográficos
Main Authors: Gros, Jerome, Tabin, Clifford J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4097009/
https://ncbi.nlm.nih.gov/pubmed/24626928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1248228
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