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β-catenin activation regulates tissue growth non-cell autonomously in the hair stem cell niche

Wnt/β-catenin signaling is critical for tissue regeneration. However, it is unclear how β-catenin controls stem cell behaviors to coordinate organized growth. Using live imaging, we show that activation of β-catenin specifically within mouse hair follicle stem cells generates new hair growth through...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Deschene, Elizabeth R., Myung, Peggy, Rompolas, Panteleimon, Zito, Giovanni, Sun, Thomas Yang, Taketo, Makoto M., Saotome, Ichiko, Greco, Valentina
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096864/
https://ncbi.nlm.nih.gov/pubmed/24653033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1248373
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