The metabolic phenotype of SCD1-deficient mice is independent of melanin-concentrating hormone

We propose that deletion of pro-melanin-concentrating hormone (pMCH) would increase energy expenditure and further improve glucose tolerance in mice lacking stearoyl-coA desaturase-1 (SCD1). To test our hypothesis, we bred and metabolically challenged Pmch−/−; Scd1−/− double-knockout mice, with comp...

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Detalhes bibliográficos
Main Authors: Glier, Melissa B., Pissios, Pavlos, Babich, Sandra L., Macdonald, Marcia L.E., Hayden, Michael R., Maratos-Flier, Eleftheria, Gibson, William T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096855/
https://ncbi.nlm.nih.gov/pubmed/19883709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2009.10.018
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