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Bioengineering radioresistance by overproduction of RPA, a mammalian-type single-stranded DNA-binding protein, in a halophilic archaeon

Halobacterium sp. NRC-1 is a wild-type extremophilic microbe that is naturally tolerant to high levels of ionizing radiation. Mutants of strain NRC-1 with even higher levels of resistance to ionizing radiation, named RAD, were previously isolated after selecting survival to extremely high-doses of i...

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Detalhes bibliográficos
Main Authors: Karan, Ram, DasSarma, Priya, Balcer-Kubiczek, Elizabeth, Weng, Rueyhung Roc, Liao, Chen-Chung, Goodlett, David R., Ng, Wailap Victor, DasSarma, Shiladitya
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096848/
https://ncbi.nlm.nih.gov/pubmed/24292079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00253-013-5368-x
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