Single nucleotide polymorphisms in nucleotide excision repair genes, cancer treatment, and head and neck cancer survival

PURPOSE: Head and neck cancers (HNC) are commonly treated with radiation and platinum-based chemotherapy, which produce bulky DNA adducts to eradicate cancerous cells. Because nucleotide excision repair (NER) enzymes remove adducts, variants in NER genes may be associated with survival among HNC cas...

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Main Authors: Wyss, Annah B., Weissler, Mark C., Avery, Christy L., Herring, Amy H., Bensen, Jeannette T., Barnholtz-Sloan, Jill S., Funkhouser, William K., Olshan, Andrew F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096829/
https://ncbi.nlm.nih.gov/pubmed/24487794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10552-014-0346-x
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