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Actin realignment and cofilin regulation are essential for barrier integrity during shear stress

Vascular endothelial cells and their actin microfilaments align in the direction of fluid shear stress (FSS) in vitro and in vivo. To determine whether cofilin, an actin severing protein, is required in this process, the levels of phospho-cofilin (serine-3) were evaluated in cells exposed to FSS. Ph...

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Detalhes bibliográficos
Main Authors: Slee, Joshua B., Lowe-Krentz, Linda J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096802/
https://ncbi.nlm.nih.gov/pubmed/23060131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.24416
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