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A cross-disciplinary perspective on the innate immune responses to bacterial lipopolysaccharide

The study of innate immunity to bacteria has focused heavily on the mechanisms by which mammalian cells detect lipopolysaccharide (LPS), the conserved surface component of gram-negative bacteria. While Toll-like Receptor 4 (TLR4) is responsible for all the host transcriptional responses to LPS, rece...

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Detalles Bibliográficos
Main Authors: Tan, Yunhao, Kagan, Jonathan C
Formato: Artigo
Idioma:Inglês
Publicado: 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096783/
https://ncbi.nlm.nih.gov/pubmed/24766885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.03.012
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