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Integrative analysis of differential miRNA and functional study of miR-21 by seed-targeting inhibition in multiple myeloma cells in response to berberine

BACKGROUND: Berberine is a natural alkaloid derived from a traditional Chinese herbal medicine. It is known to modulate microRNA (miRNA) levels, although the mechanism for this action is unknown. Here, we previously demonstrate that the expression of 87 miRNAs is differentially affected by berberine...

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Detalhes bibliográficos
Main Authors: Luo, Xiaochuang, Gu, Jingyi, Zhu, Rongxuan, Feng, Maoxiao, Zhu, Xuejiao, Li, Yumin, Fei, Jia
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096730/
https://ncbi.nlm.nih.gov/pubmed/25000828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-8-82
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