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Steering tumor progression through the transcriptional response to growth factors and stroma

Tumor progression can be understood as a collaborative effort of mutations and growth factors, which propels cell proliferation and matrix invasion, and also enables evasion of drug-induced apoptosis. Concentrating on EGFR, we discuss downstream signaling and the initiation of transcriptional events...

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Detalhes bibliográficos
Main Authors: Feldman, Morris E., Yarden, Yosef
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096583/
https://ncbi.nlm.nih.gov/pubmed/24873881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2014.05.036
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