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TCR Microclusters Preexist and Contain Molecules Necessary for TCR Signal Transduction ()

TCR-dependent signaling events have been observed to occur in TCR microclusters. We found that some TCR microclusters are present in unstimulated murine T cells, indicating that the mechanisms leading to microcluster formation do not require ligand binding. These preexisting microclusters increase i...

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Detalhes bibliográficos
Main Authors: Crites, Travis J, Padhan, Kartika, Muller, James, Krogsgaard, Michelle, Gudla, Prabhakar R., Lockett, Stephen J., Varma, Rajat
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096552/
https://ncbi.nlm.nih.gov/pubmed/24860189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400315
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