Evaluation of the Induction of Immune Memory following Infant Immunisation with Serogroup C Neisseria meningitidis Conjugate Vaccines – Exploratory Analyses within a Randomised Controlled Trial

AIM: We measured meningococcal serogroup C (MenC)-specific memory B-cell responses in infants by Enzyme-Linked Immunospot (ELISpot) following different MenC conjugate vaccine schedules to investigate the impact of priming on immune memory. METHODS: Infants aged 2 months were randomised to receive 1...

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Main Authors: Khatami, Ameneh, Clutterbuck, Elizabeth A., Thompson, Amber J., McKenna, Jennifer A., Pace, David, Birks, Jacqueline, Snape, Matthew D., Pollard, Andrew J.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
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Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096514/
https://ncbi.nlm.nih.gov/pubmed/25020050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101672
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