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Pten Loss in Olig2 Expressing Neural Progenitor Cells and Oligodendrocytes Leads to Interneuron Dysplasia and Leukodystrophy

Therapeutic modulation of PI3K/PTEN signaling is currently being explored for multiple neurological indications including brain tumors and seizure disorders associated with cortical malformations. The effects of PI3K/PTEN signaling are highly cell context dependent but the function of this pathway i...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Maire, Cécile L., Ramkissoon, Shakti, Hayashi, Marika, Haidar, Sam, Ramkissoon, Lori, DiTomaso, Emmanuelle, Ligon, Keith L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096461/
https://ncbi.nlm.nih.gov/pubmed/24395742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1590
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