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Blk-Haploinsufficiency Impairs the Development, but Enhances the Functional Responses, of MZ B Cells

Blk was identified two decades ago as a B cell-specific member of the Src family of tyrosine kinases. Recent studies, however, have discovered that Blk is expressed in many cell types outside of the B lineage, including early thymic precursors, IL-17-producing γδ T cells and pancreatic β-cells. In l...

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Detalhes bibliográficos
Main Authors: Samuelson, Elizabeth M., Laird, Renee M., Maue, Alexander C., Rochford, Rosemary, Hayes, Sandra M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096015/
https://ncbi.nlm.nih.gov/pubmed/21894171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2011.76
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