Aliskiren and Valsartan Mediate Left Ventricular Remodeling Post-Myocardial Infarction in Mice through MMP-9 Effects

BACKGROUND: We evaluated whether aliskiren, valsartan, or the combination was protective following myocardial infarction (MI) through effects on matrix metalloproteinase (MMP)-9. METHODS AND RESULTS: C57BL/6J wild type (WT, n=94) and MMP-9 null (null, n=85) mice were divided into 4 groups at 3 h pos...

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Detalhes bibliográficos
Main Authors: Ramirez, Trevi A., Iyer, Rugmani Padmanabhan, Ghasemi, Omid, Lopez, Elizabeth F., Levin, Daniel B., Zhang, Jianhua, Zamilpa, Rogelio, Chou, Youn-Min, Jin, Yu-Fang, Lindsey, Merry L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4095995/
https://ncbi.nlm.nih.gov/pubmed/24768766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2014.04.007
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