The transcription factor Pou3f1 promotes neural fate commitment via activation of neural lineage genes and inhibition of external signaling pathways

The neural fate commitment of pluripotent stem cells requires the repression of extrinsic inhibitory signals and the activation of intrinsic positive transcription factors. However, how these two events are integrated to ensure appropriate neural conversion remains unclear. In this study, we showed...

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Detalhes bibliográficos
Main Authors: Zhu, Qingqing, Song, Lu, Peng, Guangdun, Sun, Na, Chen, Jun, Zhang, Ting, Sheng, Nengyin, Tang, Wei, Qian, Cheng, Qiao, Yunbo, Tang, Ke, Han, Jing-Dong Jackie, Li, Jinsong, Jing, Naihe
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2014
Assuntos:
Developmental Biology and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4095939/
https://ncbi.nlm.nih.gov/pubmed/24929964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02224
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