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Gd(DOTAlaP): Exploring the Boundaries of Fast Water Exchange in Gadolinium-Based Magnetic Resonance Imaging Contrast Agents

[Image: see text] Here, we describe the synthesis of the single amino acid chelator DOTAlaP and four of its derivatives. The corresponding gadolinium(III) complexes were investigated for their kinetic inertness, relaxometric properties at a range of fields and temperatures, water exchange rate, and...

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Detalhes bibliográficos
Main Authors: Boros, Eszter, Karimi, Shima, Kenton, Nathaniel, Helm, Lothar, Caravan, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4095929/
https://ncbi.nlm.nih.gov/pubmed/24922178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ic5008928
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