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Metabolic requirements for the maintenance of self-renewing stem cells

A distinctive feature of stem cells is their capacity to self-renew to maintain pluripotency. Studies of genetically-engineered mouse models and recent advances in metabolomic analysis, particularly in haematopoietic stem cells, have deepened our understanding of the contribution made by metabolic c...

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Bibliografiske detaljer
Main Authors: Ito, Keisuke, Suda, Toshio
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4095859/
https://ncbi.nlm.nih.gov/pubmed/24651542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm3772
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