Therapeutic safety of high myocardial expression levels of the molecular inotrope S100A1 in a preclinical heart failure model

Low levels of the molecular inotrope S100A1 are sufficient to rescue post-ischemic heart failure (HF). As a prerequisite to clinical application and to determine the safety of myocardial S100A1 DNA-based therapy, we investigated the effects of high myocardial S100A1 expression levels on the cardiac...

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Detalhes bibliográficos
Main Authors: Weber, C, Neacsu, I, Krautz, B, Schlegel, P, Sauer, S, Raake, P, Ritterhoff, J, Jungmann, A, Remppis, AB, Stangassinger, M, Koch, WJ, Katus, HA, Müller, OJ, Most, P, Pleger, ST
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4095772/
https://ncbi.nlm.nih.gov/pubmed/24305416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2013.63
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