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Alzheimer’s disease drug-development pipeline: few candidates, frequent failures

INTRODUCTION: Alzheimer’s disease (AD) is increasing in frequency as the global population ages. Five drugs are approved for treatment of AD, including four cholinesterase inhibitors and an N-methyl-D-aspartate (NMDA)-receptor antagonist. We have an urgent need to find new therapies for AD. METHODS:...

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Bibliografiske detaljer
Main Authors: Cummings, Jeffrey L, Morstorf, Travis, Zhong, Kate
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4095696/
https://ncbi.nlm.nih.gov/pubmed/25024750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/alzrt269
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