Integrated assessment of predicted MHC binding and cross-conservation with self reveals patterns of viral camouflage

BACKGROUND: Immune recognition of foreign proteins by T cells hinges on the formation of a ternary complex sandwiching a constituent peptide of the protein between a major histocompatibility complex (MHC) molecule and a T cell receptor (TCR). Viruses have evolved means of "camouflaging" th...

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Bibliografiske detaljer
Main Authors: He, Lu, De Groot, Anne S, Gutierrez, Andres H, Martin, William D, Moise, Lenny, Bailey-Kellogg, Chris
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094998/
https://ncbi.nlm.nih.gov/pubmed/25104221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-15-S4-S1
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