Genome-wide Functional Analysis of Plasmodium Protein Phosphatases Reveals Key Regulators of Parasite Development and Differentiation

Reversible protein phosphorylation regulated by kinases and phosphatases controls many cellular processes. Although essential functions for the malaria parasite kinome have been reported, the roles of most protein phosphatases (PPs) during Plasmodium development are unknown. We report a functional a...

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Detalhes bibliográficos
Main Authors: Guttery, David S., Poulin, Benoit, Ramaprasad, Abhinay, Wall, Richard J., Ferguson, David J.P., Brady, Declan, Patzewitz, Eva-Maria, Whipple, Sarah, Straschil, Ursula, Wright, Megan H., Mohamed, Alyaa M.A.H., Radhakrishnan, Anand, Arold, Stefan T., Tate, Edward W., Holder, Anthony A., Wickstead, Bill, Pain, Arnab, Tewari, Rita
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094981/
https://ncbi.nlm.nih.gov/pubmed/25011111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2014.05.020
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