Abnormal urinary excretion of NKCC2 and AQP2 in response to hypertonic saline in chronic kidney disease: an intervention study in patients with chronic kidney disease and healthy controls

BACKGROUND: Renal handling of sodium and water is abnormal in chronic kidney disease (CKD). The aim of this study was to test the hypothesis that abnormal activity of the aquaporin-2 water channels (AQP2), the sodium-potassium-2chloride transporter (NKCC2) and/or the epithelial sodium channels (ENaC...

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Bibliographic Details
Main Authors: Jensen, Janni M, Mose, Frank H, Kulik, Anna-Ewa O, Bech, Jesper N, Fenton, Robert A, Pedersen, Erling B
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094915/
https://ncbi.nlm.nih.gov/pubmed/24970686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2369-15-101
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