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Sinefungin, a Natural Nucleoside Analogue of S-Adenosylmethionine, Inhibits Streptococcus pneumoniae Biofilm Growth

Pneumococcal colonization and disease is often associated with biofilm formation, in which the bacteria exhibit elevated resistance both to antibiotics and to host defense systems, often resulting in infections that are persistent and difficult to treat. We evaluated the effect of sinefungin, a nucl...

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Autors principals: Yadav, Mukesh Kumar, Park, Seok-Won, Chae, Sung-Won, Song, Jae-Jun
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094849/
https://ncbi.nlm.nih.gov/pubmed/25050323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/156987
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