Pharmacological doses of niacin stimulate the expression of genes involved in carnitine uptake and biosynthesis and improve the carnitine status of obese Zucker rats

BACKGROUND: Activation of peroxisome proliferator-activated receptor (PPAR)α and PPARδ causes an elevation of tissue carnitine concentrations through induction of genes involved in carnitine uptake [novel organic cation transporter 2, (OCTN2)], and carnitine biosynthesis [γ-butyrobetaine dioxygenase...

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Hlavní autoři: Couturier, Aline, Ringseis, Robert, Most, Erika, Eder, Klaus
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094635/
https://ncbi.nlm.nih.gov/pubmed/25012467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2050-6511-15-37
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