Hepatitis C Virus Hypervariable Region 1 Variants Presented on Hepatitis B Virus Capsid-Like Particles Induce Cross-Neutralizing Antibodies

Hepatitis C virus (HCV) infection is still a serious global health burden. Despite improved therapeutic options, a preventative vaccine would be desirable especially in undeveloped countries. Traditionally, highly conserved epitopes are targets for antibody-based prophylactic vaccines. In HCV-infect...

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Detalhes bibliográficos
Main Authors: Lange, Milena, Fiedler, Melanie, Bankwitz, Dorothea, Osburn, William, Viazov, Sergei, Brovko, Olena, Zekri, Abdel-Rahman, Khudyakov, Yury, Nassal, Michael, Pumpens, Paul, Pietschmann, Thomas, Timm, Jörg, Roggendorf, Michael, Walker, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094522/
https://ncbi.nlm.nih.gov/pubmed/25014219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102235
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