Validation of a LC-MS/MS Method for Quantifying Urinary Nicotine, Six Nicotine Metabolites and the Minor Tobacco Alkaloids—Anatabine and Anabasine—in Smokers' Urine

Tobacco use is a major contributor to premature morbidity and mortality. The measurement of nicotine and its metabolites in urine is a valuable tool for evaluating nicotine exposure and for nicotine metabolic profiling—i.e., metabolite ratios. In addition, the minor tobacco alkaloids—anabasine and a...

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Main Authors: McGuffey, James E., Wei, Binnian, Bernert, John T., Morrow, John C., Xia, Baoyun, Wang, Lanqing, Blount, Benjamin C.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2014
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094486/
https://ncbi.nlm.nih.gov/pubmed/25013964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101816
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