Systemic Treatment with Erythropoietin Protects the Neurovascular Unit in a Rat Model of Retinal Neurodegeneration

Rats expressing a transgenic polycystic kidney disease (PKD) gene develop photoreceptor degeneration and subsequent vasoregression, as well as activation of retinal microglia and macroglia. To target the whole neuroglialvascular unit, neuro- and vasoprotective Erythropoietin (EPO) was intraperitonea...

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Detalhes bibliográficos
Main Authors: Busch, Stephanie, Kannt, Aimo, Kolibabka, Matthias, Schlotterer, Andreas, Wang, Qian, Lin, Jihong, Feng, Yuxi, Hoffmann, Sigrid, Gretz, Norbert, Hammes, Hans-Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094460/
https://ncbi.nlm.nih.gov/pubmed/25013951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102013
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