Genetic analysis of an allergic rhinitis cohort reveals an intercellular epistasis between FAM134B and CD39

BACKGROUND: Extracellular ATP is a pro-inflammatory molecule released by damaged cells. Regulatory T cells (Treg) can suppress inflammation by hydrolysing this molecule via ectonucleoside triphosphate diphosphohydrolase 1 (ENTPD1), also termed as CD39. Multiple studies have reported differences in C...

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Detalhes bibliográficos
Main Authors: Melchiotti, Rossella, Puan, Kia Joo, Andiappan, Anand Kumar, Poh, Tuang Yeow, Starke, Mireille, Zhuang, Li, Petsch, Kerstin, Lai, Tuck Siong, Chew, Fook Tim, Larbi, Anis, Wang, De Yun, Poidinger, Michael, Rotzschke, Olaf
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094447/
https://ncbi.nlm.nih.gov/pubmed/24970562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-15-73
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