Myeloid Derived Suppressor Cells (MDSCs) Are Increased and Exert Immunosuppressive Activity Together with Polymorphonuclear Leukocytes (PMNs) in Chronic Myeloid Leukemia Patients

Tumor immune tolerance can derive from the recruitment of suppressor cell population, including myeloid derived suppressor cells (MDSCs), able to inhibit T cells activity. We identified a significantly expanded MDSCs population in chronic myeloid leukemia (CML) patients at diagnosis that decreased t...

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Main Authors: Giallongo, Cesarina, Parrinello, Nunziatina, Tibullo, Daniele, La Cava, Piera, Romano, Alessandra, Chiarenza, Annalisa, Barbagallo, Ignazio, Palumbo, Giuseppe A., Stagno, Fabio, Vigneri, Paolo, Di Raimondo, Francesco
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094386/
https://ncbi.nlm.nih.gov/pubmed/25014230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101848
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