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Bioreductively Activated Reactive Oxygen Species (ROS) Generators as MRSA Inhibitors

[Image: see text] The number of cases of drug resistant Staphylococcus aureus infections is on the rise globally and new strategies to identify drug candidates with novel mechanisms of action are in urgent need. Here, we report the synthesis and evaluation of a series of benzo[b]phenanthridine-5,7,1...

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Detalhes bibliográficos
Main Authors: Khodade, Vinayak S., Sharath Chandra, Mallojjala, Banerjee, Ankita, Lahiri, Surobhi, Pulipeta, Mallikarjuna, Rangarajan, Radha, Chakrapani, Harinath
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094247/
https://ncbi.nlm.nih.gov/pubmed/25050164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml5001118
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