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Activation of the PKC Pathway Stimulates Ovarian Cancer Cell Proliferation, Migration, and Expression of MMP7 and MMP10

Postmenopausal women are at a higher risk of ovarian cancer due, in part, to increased levels of gonadotropins such as luteinizing hormone (LH). Gonadotropins and other stimuli are capable of activating two pathways, PKA and PKC, that are altered in ovarian cancer. To determine the role of LH on ova...

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Autors principals: Al-Alem, Linah F., McCord, Lauren A., Southard, R. Chase, Kilgore, Michael W., Curry, Thomas E.
Format: Artigo
Idioma:Inglês
Publicat: Society for the Study of Reproduction, Inc. 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094197/
https://ncbi.nlm.nih.gov/pubmed/23843242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.112.102327
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