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Urinary kidney biomarkers for early detection of nephrotoxicity in clinical drug development
Early detection of drug-induced kidney injury is vital in drug development. Generally accepted biomarkers such as creatinine and blood urea nitrogen (BUN) lack sensitivity and early injury responses are missed. Many new biomarkers to detect nephrotoxicity for pre-clinical utilization have been descr...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Blackwell Science Inc
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4093920/ https://ncbi.nlm.nih.gov/pubmed/24219059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12282 |
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