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Alpha/Beta Interferon Receptor Signaling Amplifies Early Proinflammatory Cytokine Production in the Lung during Respiratory Syncytial Virus Infection

Type I interferons (IFNs) are produced early upon virus infection and signal through the alpha/beta interferon (IFN-α/β) receptor (IFNAR) to induce genes that encode proteins important for limiting viral replication and directing immune responses. To investigate the extent to which type I IFNs play...

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Main Authors: Goritzka, Michelle, Durant, Lydia R., Pereira, Catherine, Salek-Ardakani, Samira, Openshaw, Peter J. M., Johansson, Cecilia
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4093897/
https://ncbi.nlm.nih.gov/pubmed/24648449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00333-14
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