The Thr205 Phosphorylation Site within Respiratory Syncytial Virus Matrix (M) Protein Modulates M Oligomerization and Virus Production

Human respiratory syncytial virus (RSV) is the most common cause of bronchiolitis and pneumonia in infants and the elderly worldwide; however, there is no licensed RSV vaccine or effective drug treatment available. The RSV matrix (M) protein plays key roles in virus assembly and budding, but the pro...

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Autors principals: Bajorek, M., Caly, L., Tran, K. C., Maertens, G. N., Tripp, R. A., Bacharach, E., Teng, M. N., Ghildyal, R., Jans, D. A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
Matèries:
Structure and Assembly
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4093874/
https://ncbi.nlm.nih.gov/pubmed/24672034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03856-13
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