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Pseudorabies Virus pUL46 Induces Activation of ERK1/2 and Regulates Herpesvirus-Induced Nuclear Envelope Breakdown

Herpesvirus capsid morphogenesis occurs in the nucleus, while final maturation takes place in the cytosol, requiring translocation of capsids through the nuclear envelope. The nuclear egress complex, consisting of homologs of herpes simplex virus pUL31 and pUL34, is required for efficient nuclear eg...

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Autors principals: Schulz, Katharina S., Liu, XueQiao, Klupp, Barbara G., Granzow, Harald, Cohen, Jeffrey I., Mettenleiter, Thomas C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4093849/
https://ncbi.nlm.nih.gov/pubmed/24623429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00501-14
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