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In silico comparative characterization of pharmacogenomic missense variants
BACKGROUND: Missense pharmacogenomic (PGx) variants refer to amino acid substitutions that potentially affect the pharmacokinetic (PK) or pharmacodynamic (PD) response to drug therapies. The PGx variants, as compared to disease-associated variants, have not been investigated as deeply. The ability t...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4092878/ https://ncbi.nlm.nih.gov/pubmed/25057096 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-S4-S4 |
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