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Molecular evolution of the enzymes involved in the sphingolipid metabolism of Leishmania: selection pressure in relation to functional divergence and conservation

BACKGROUND: Selection pressure governs the relative mutability and the conservedness of a protein across the protein family. Biomolecules (DNA, RNA and proteins) continuously evolve under the effect of evolutionary pressure that arises as a consequence of the host parasite interaction. IPCS (Inosito...

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Detalhes bibliográficos
Main Authors: Mandlik, Vineetha, Shinde, Sonali, Singh, Shailza
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4092354/
https://ncbi.nlm.nih.gov/pubmed/24951280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-14-142
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