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BRCA1 Induces Major Energetic Metabolism Reprogramming in Breast Cancer Cells

The hypermetabolic nature of cancer cells and their increased reliance on “aerobic glycolysis”, as originally described by Otto Warburg and colleagues, are considered metabolic hallmarks of cancer cells. BRCA1 is a major tumor suppressor in breast cancer and it was implicated in numerous pathways re...

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Detalhes bibliográficos
Main Authors: Privat, Maud, Radosevic-Robin, Nina, Aubel, Corinne, Cayre, Anne, Penault-Llorca, Frédérique, Marceau, Geoffroy, Sapin, Vincent, Bignon, Yves-Jean, Morvan, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4092140/
https://ncbi.nlm.nih.gov/pubmed/25010005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102438
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