The mtDNA nt7778 G/T Polymorphism Augments Formation of Lymphocytic Foci but Does Not Aggravate Cerulein-Induced Acute Pancreatitis in Mice

A polymorphism in the ATP synthase 8 (ATP8) gene of the murine mitochondrial genome, G-to-T transversion at position 7778, has been suggested to increase susceptibility to multiple autoimmune diseases, including autoimmune pancreatitis (AIP). The polymorphism also induces mitochondrial reactive oxyg...

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Detalhes bibliográficos
Main Authors: Müller, Sarah, Krüger, Burkhard, Lange, Falko, Bock, Cristin N., Nizze, Horst, Glass, Änne, Ibrahim, Saleh M., Jaster, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4092110/
https://ncbi.nlm.nih.gov/pubmed/25010670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102266
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