Anti-Epileptic Effect of Ganoderma Lucidum Polysaccharides by Inhibition of Intracellular Calcium Accumulation and Stimulation of Expression of CaMKII α in Epileptic Hippocampal Neurons

PURPOSE: To investigate the mechanism of the anti-epileptic effect of Ganoderma lucidum polysaccharides (GLP), the changes of intracellular calcium and CaMK II α expression in a model of epileptic neurons were investigated. METHOD: Primary hippocampal neurons were divided into: 1) Control group, neu...

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Detalhes bibliográficos
Main Authors: Wang, Shu-Qiu, Li, Xiao-Jie, Qiu, Hong-Bin, Jiang, Zhi-Mei, Simon, Maria, Ma, Xiao-Ru, Liu, Lei, Liu, Jun-Xing, Wang, Fang-Fang, Liang, Yan-Feng, Wu, Jia-Mei, Di, Wei-Hua, Zhou, Shaobo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4092074/
https://ncbi.nlm.nih.gov/pubmed/25010576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102161
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