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The hedgehog’s trick for escaping immunosurveillance: The molecular mechanisms driving myeloid-derived suppressor cell recruitment in hedgehog signaling-dependent tumors

Myeloid-derived suppressor cells (MDSCs) are an important means by which tumor cells evade immunosurveillance. Here, we set out to determine how MDSCs are recruited to tumors in genetically engineered mouse cancer models. Expression of oncogenic and constitutively active SmoM2, a key hedgehog-signal...

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Bibliografische gegevens
Hoofdauteur: Xie, Jingwu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Landes Bioscience 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4092004/
https://ncbi.nlm.nih.gov/pubmed/25054089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.29180
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