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Aggression-reducing effects of F15599, a novel selective 5-HT(1A) receptor agonist, after microinjection into the ventral orbital prefrontal cortex, but not in infralimbic cortex in male mice
BACKGROUND: The 5-HT(1A) receptor subtype has been postulated to modulate aggressive behavior particularly when it is excessive. F15599 is a high affinity and selective 5-HT(1A) receptor agonist that exhibits biased agonism for postsynaptic receptors that are preferentially coupled to Gαi3 protein s...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4091917/ https://ncbi.nlm.nih.gov/pubmed/23828155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-013-3164-z |
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