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Role of the loop L(4,5) in allosteric regulation in mtHsp70s: in vivo significance of domain communication and its implications in protein translocation

Mitochondrial Hsp70 (mtHsp70) is essential for a vast repertoire of functions, including protein import, and requires effective interdomain communication for efficient partner-protein interactions. However, the in vivo functional significance of allosteric regulation in eukaryotes is poorly defined....

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Detalhes bibliográficos
Main Authors: Samaddar, Madhuja, Goswami, Arvind Vittal, Purushotham, Jaya, Hegde, Pushpa, D'Silva, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4091826/
https://ncbi.nlm.nih.gov/pubmed/24829379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-03-0821
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