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A New Lnc in Metastasis: Long Non-Coding RNA Mediates the Pro-metastatic Functions of TGF-β
TGF-β signaling promotes metastasis by controlling the expression of downstream target genes. In this issue of Cancer Cell, Yuan et al. discover a novel TGF-β-induced lncRNA, lncRNA-ATB, that stimulates EMT through sequestering miR-200s and facilitates colonization by stabilizing IL-11 mRNA, thus pr...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4091806/ https://ncbi.nlm.nih.gov/pubmed/24823634 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2014.04.014 |
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