Mesenteric lymph diversion abrogates 5-lipoxygenase activation in the kidney following trauma and hemorrhagic shock

BACKGROUND: Early acute kidney injury (AKI) following trauma is associated with multiorgan failure and mortality. Leukotrienes have been implicated both in AKI and in acute lung injury. Activated 5-lipoxygenase (5-LO) colocalizes with 5-LO–activating protein (FLAP) in the first step of leukotriene p...

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Main Authors: Stringham, John R., Moore, Ernest E., Gamboni, Fabia, Harr, Jeffrey N., Fragoso, Miguel, Chin, Theresa L., Carr, Caitlin E., Silliman, Christopher C., Banerjee, Anirban
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4091733/
https://ncbi.nlm.nih.gov/pubmed/24747451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TA.0000000000000231
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