γδ T cells recognize the insulin B:9-23 peptide antigen when it is dimerized through thiol oxidation()

The insulin peptide B:9-23 is a natural antigen in the non-obese diabetic (NOD) mouse model of type 1 diabetes (T1D). In addition to αβ T cells and B cells, γδ T cells recognize the peptide and infiltrate the pancreatic islets where the peptide is produced within β cells. The peptide contains a cyst...

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Main Authors: Aydintug, M. Kemal, Zhang, Li, Wang, Chao, Liang, Dongchun, Wands, J.M., Michels, Aaron W, Hirsch, Brooke, Day, Brian J., Zhang, Gongyi, Sun, Deming, Eisenbarth, George S., O'Brien, Rebecca L., Born, Willi K.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4091716/
https://ncbi.nlm.nih.gov/pubmed/24853397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2014.04.007
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