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Characterization and Application of the Fe(II) and α-Ketoglutarate Dependent Hydroxylase FrbJ
The Fe(II) and α-ketoglutarate-dependent hydroxylase FrbJ was previously demonstrated to utilize FR-900098 synthesizing a second phosphonate FR-33289. Here we assessed its ability to hydroxylate other possible substrates, generating a library of potential antimalarial compounds. Through a series of...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4091617/ https://ncbi.nlm.nih.gov/pubmed/21829824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c1cc13597j |
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