Dolutegravir in Antiretroviral-Experienced Patients With Raltegravir- and/or Elvitegravir-Resistant HIV-1: 24-Week Results of the Phase III VIKING-3 Study

Background. The pilot phase IIb VIKING study suggested that dolutegravir (DTG), a human immunodeficiency virus (HIV) integrase inhibitor (INI), would be efficacious in INI-resistant patients at the 50 mg twice daily (BID) dose. Methods. VIKING-3 is a single-arm, open-label phase III study in which t...

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Detalhes bibliográficos
Main Authors: Castagna, Antonella, Maggiolo, Franco, Penco, Giovanni, Wright, David, Mills, Anthony, Grossberg, Robert, Molina, Jean-Michel, Chas, Julie, Durant, Jacques, Moreno, Santiago, Doroana, Manuela, Ait-Khaled, Mounir, Huang, Jenny, Min, Sherene, Song, Ivy, Vavro, Cindy, Nichols, Garrett, Yeo, Jane M., Aberg, J., Akil, B., Arribas, J. R., Baril, J.-G., Blanco Arévalo, J. L., Blanco Quintana, F., Blick, G., Boix Martínez, V., Bouchaud, O., Branco, T., Bredeek, U. F., Castro Iglesias, M., Clumeck, N., Conway, B., DeJesus, E., Delassus, J.-L., De Truchis, P., Di Perri, G., Di Pietro, M., Duggan, J., Duvivier, C., Elion, R., Eron, J., Fish, D., Gathe, J., Haubrich, R., Henderson, H., Hicks, C., Hocqueloux, L., Hodder, S., Hsiao, C.-B., Katlama, C., Kozal, M., Kumar, P., Lalla-Reddy, S., Lazzarin, A., Leoncini, F., Llibre, J. M., Mansinho, K., Morlat, P., Mounzer, K., Murphy, M., Newman, C., Nguyen, T., Nseir, B., Philibert, P., Pialoux, G., Poizot-Martin, I., Ramgopal, M., Richmond, G., Salmon Ceron, D., Sax, P., Scarsella, A., Sension, M., Shalit, P., Sighinolfi, L., Sloan, L., Small, C., Stein, D., Tashima, K., Tebas, P., Torti, C., Tribble, M., Troisvallets, D., Tsoukas, C., Viciana Fernández, P., Ward, D., Wheeler, D., Wilkin, T., Yeni, G.-P., Louise Martin-Carpenter, J., Uhlenbrauck, Gina
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4091579/
https://ncbi.nlm.nih.gov/pubmed/24446523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu051
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