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ABC transporters in CSCs membranes as a novel target for treating tumor relapse

CSCs are responsible for the high rate of recurrence and chemoresistance of different types of cancer. The current antineoplastic agents able to inhibit bulk replicating cancer cells and radiation treatment are not efficacious toward CSCs since this subpopulation has several intrinsic mechanisms of...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zinzi, Laura, Contino, Marialessandra, Cantore, Mariangela, Capparelli, Elena, Leopoldo, Marcello, Colabufo, Nicola A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4091306/
https://ncbi.nlm.nih.gov/pubmed/25071581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2014.00163
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